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Cannabidiol (CBD), a main component of medical cannabis, has witnessed a surge in popularity in recent years, with consumers keen to explore its wide range of potential therapeutic opportunities and benefits.
Among the abundance of CBD products on the market, CBD cream stands out as a go-to for those seeking localised relief from joint or muscle pain, inflammation, and various skin disorders, such as eczema, psoriasis. Read the article here on CBD for pain. https://pmc.ncbi.nlm.nih.gov/articles/PMC7204604/
As research on cannabis and its derivatives expands, CBD has become a key focus, particularly for those seeking natural alternatives to manage various health issues. Unlike its psychoactive counterpart, tetrahydrocannabinol (THC), CBD does not produce a “high”, making it an attractive option for individuals who want the potential healing properties of cannabis without the mind-altering effects. But what exactly does CBD cream do to your body and how does it work? Let’s explore…
CBD cream is a topical product infused with cannabidiol (CBD), a compound from the Cannabis plant. Unlike tetrahydrocannabinol (THC) which is responsible for the psychoactive effects of marijuana, CBD is non-psychoactive and has more of a therapeutic effect for pain relief.
CBD creams are made by mixing CBD extract with a base of moisturising agents like shea butter and essential oils. The result is a product you can apply directly to your skin for potential benefits.
CBD creams may come in different varieties, including:
CBD-infused balms: Thicker and more concentrated, designed for more intense pain relief.
CBD lotions: More lightweight, with added hydration benefits, suitable for larger surface areas.
CBD roll-ons or ointments: Designed for precise application, often with a cooling or warming sensation.
Unlike CBD oils, tinctures or edibles which are ingested and processed through the digestive system, CBD creams are applied directly to the skin. This allows the CBD to target specific areas of discomfort like sore muscles or inflamed skin making it a more localised treatment option. The key difference here is that CBD cream doesn’t enter the bloodstream in significant amounts like edibles or oils would, so the effects are confined to the application area.
To understand how CBD cream affects the body, it’s essential to first understand the endocannabinoid system (ECS) and this is why many people ask how does CBD work?. The ECS is a complex biological system that plays a critical role in maintaining balance, or homeostasis, in the body. Research shows it could be involved in regulating various physiological processes such as:
The ECS comprises three main components:
CBD uniquely interacts with the ECS. Unlike THC, which binds directly to CB1 receptors to create psychoactive effects, CBD has an indirect impact. It modulates the activity of the ECS by:
Inhibiting enzymes that break down endocannabinoids, allowing them to remain active for longer.
Interacting with non-cannabinoid receptors, such as serotonin receptors, which play a role in pain perception and inflammation.
This complex interaction means that CBD may help regulate pain, reduce inflammation, and support skin health, even when applied topically through creams.
The skin is the body’s largest organ and serves as a barrier. It does a great job of keeping most things out but it can still absorb certain compounds especially those that are lipid soluble like CBD. When applied to the skin CBD interacts with endocannabinoid receptors in the skin’s layers without entering the bloodstream in significant amounts.
This absorption allows for a localised effect, so if you apply CBD cream to your joints for arthritis pain the effects are in that area not throughout your whole body.
Because CBD cream typically doesn’t penetrate deep enough to enter the bloodstream in large quantities, the effects are primarily localised. This makes CBD cream an appealing option for individuals looking to manage specific areas of discomfort, such as a sore knee, a muscle strain, or skin irritation.
In contrast, ingesting CBD oil or capsules can provide more systemic effects, meaning they impact the entire body, which may be more suitable for individuals dealing with neurological issues like anxiety or insomnia.
CBD cream is used mainly for pain relief, especially for conditions involving musculoskeletal pain, such as arthritis, back pain, or general soreness from physical activity. This doesn’t guarantee pain relief but many people use it as a natural pain relief as some studies show cbd can help pain relief. The pain-relieving properties of CBD are attributed to its interaction with cannabinoid receptors in the skin, which may help reduce pain signals sent to the brain.
CBD may also reduce pain perception by interacting with non-cannabinoid receptors, such as TRPV1 receptors, which are involved in the body’s response to pain and inflammation. For example, some individuals with arthritis have reported that their joint pain has reduced after consistently applying CBD cream, giving them improved mobility and a better quality of life.
Inflammation is a natural immune response, but chronic inflammation can lead to pain, discomfort, and long-term health issues. CBD has demonstrated anti-inflammatory properties in various studies, making it an option for individuals suffering from conditions characterised by inflammation, such as arthritis, tendonitis, and inflammatory skin diseases.
When applied topically, CBD can help reduce inflammation in the targeted area, leading to decreased swelling, redness, and discomfort. This is particularly beneficial for athletes or individuals recovering from injuries, as CBD cream can aid in muscle recovery by reducing post-exercise inflammation.
Beyond pain relief, CBD cream is now also being used for its potential benefits for skin health. Its anti-inflammatory, antioxidant, and soothing properties make it an attractive option for individuals dealing with a range of skin conditions, including:
Eczema: CBD may help soothe itchy, inflamed skin and reduce flare-ups.
Psoriasis: Some research suggests that CBD’s anti-inflammatory effects may help reduce the symptoms of this chronic skin condition.
Acne: CBD may help regulate oil production in the skin and reduce acne-related inflammation, making it a promising option for individuals with acne-prone skin.
Ageing: CBD is rich in antioxidants, which may help protect the skin from damage caused by free radicals, contributing to a more youthful appearance.
Athletes and avid gym-goers often use CBD cream to aid in muscle recovery and reduce post-workout soreness. After intense physical activity, muscles may become inflamed and sore. The anti-inflammatory properties of CBD cream can help reduce inflammation in overworked muscles, promoting faster recovery and reducing discomfort.
Additionally, some CBD creams are formulated with ingredients like menthol or arnica, which provide a cooling or warming sensation that can further alleviate muscle tension and soreness.
CBD cream may also be beneficial for individuals experiencing nerve pain, also known as neuropathy. Neuropathy occurs when nerves are damaged or malfunctioning, leading to sharp, shooting pain, tingling, or numbness. Research suggests that CBD may help alleviate neuropathic pain by interacting with the body’s pain receptors and reducing inflammation around the affected nerves.
Some individuals with conditions like sciatica or peripheral neuropathy have reported a reduction in pain and discomfort after using CBD cream, though more research is needed to fully understand its efficacy in treating neuropathic pain.
There is growing scientific interest in CBD’s potential to alleviate pain and reduce inflammation. While human studies are still in the early stages, animal studies and anecdotal reports suggest that CBD cream can provide relief for individuals suffering from chronic pain conditions. For example:
A 2015 study published in the European Journal of Pain found that topical CBD reduced inflammation and pain-related behaviours in rats with arthritis. https://pmc.ncbi.nlm.nih.gov/articles/PMC6746317/
A 2019 study in the Journal of Clinical Medicine highlighted CBD’s potential to alleviate chronic pain conditions, including neuropathic and inflammatory pain. https://pubmed.ncbi.nlm.nih.gov/30730563/
Though more human clinical trials are needed, these studies provide promising evidence for the effectiveness of CBD cream in managing pain and inflammation.
Research into CBD’s effects on skin health is also up and coming. For example, a 2020 study published in Clinical Therapeutics found that topical CBD improved skin health and reduced inflammation in patients with inflammatory skin diseases like psoriasis and eczema. Another study published in The Journal of Clinical Investigation found that CBD could help reduce sebum production, which may be useful in treating acne.
As interest in CBD continues to grow, more case studies and clinical trials are being conducted to explore its potential benefits. In one 2018 case study, a woman with peripheral neuropathy reported significant improvement in pain and discomfort after using a CBD-infused cream on her feet for several weeks. While case studies provide valuable insights, larger, placebo-controlled clinical trials are needed to confirm these findings.
To maximise the benefits of CBD cream, it’s important to apply it correctly. Here are a few tips:
The appropriate dosage of CBD cream will vary depending on the concentration of CBD in the product, the size of the area being treated, and individual factors such as body weight and the severity of the condition. Start with a small amount and gradually increase as needed. Be sure to follow the manufacturer’s instructions regarding dosage and application frequency.
When choosing a CBD cream, it’s important to consider factors such as:
CBD cream is a versatile and natural option for people looking for relief for localised pain, inflammation and skin conditions to see if it works for them. While the research is still growing many users are reporting positive results, especially for conditions like arthritis, muscle soreness and inflammatory skin issues. By interacting with the endocannabinoid system and providing targeted relief CBD cream can help alleviate discomfort and promote skin health without the psychoactive effects of THC.
At CBD Cream Shop, we are a leading specialist in CBD cream. We are the home to the highest quality CBD products in the UK. With an unfaltering attitude towards quality, our product are lab tested and offer the purest CBD creams available.
Check out our range of products and see what you think will work for you. With the right product and application CBD cream can be a good addition to your self-care routine, a natural way to manage pain and support skin health.
Disclaimer: The above article may contain information and references to CBD “for” a specific subject, for example, “CBD for arthritis pain”. It is important for us to be clear and confirm that CBD is an actual food supplement, while it may be useful for many people, is not sold “for” any specific purpose other than general health and wellbeing. Any references of CBD for a specific subject are simply so to clarify this to anyone searching for these terms out of interest.
Last Updated on 25th April 2026
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